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IBEB - Artigos em Conferências

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http://hdl.handle.net/10451/43596
Artigos em Conferências

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Browsing IBEB - Artigos em Conferências by Subject "Biomedical Engineering"

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  • Optics and Lasers @ IBEB
    Publication . João M. P. Coelho, Tânia Ferreira-Gonçalves; Mariana Neves Amaral, Hugo A. Ferreira; Maria Manuela Gaspar, Catarina Pinto Reis
    IBEB (Instituto de Biofísica e Engenharia Biomédica) is a research institute from Faculdade de Ciências da Universidade de Lisboa, that interfaces engineering with medicine and biophysics. Founded in 1992, it started researching into optics and lasers in 2009. Since then, two main areas emerged: the development of photothermal therapy for cancer, and the evaluation of the effects of laser dazzle. Regarding the first area, an irradiation procedure was tested considering a dedicated optical zoom system [1], besides using common direct irradiation. Currently, techniques capable of adapting to tumours’ contours are being developed. Also, a proof of concept on feedback wavefront shaping was achieved by applying adequate algorithms for concentrating light inside the tissues. Implemented in transmission, it allowed to increase the beam’s concentration inside a turbid media by 50% [2]. Experimental procedures were also implemented to support the development of metallic nanoparticles (NPs) capable of mediating the conversion of the energy from photons into heat. So far, the gold NPs showed to have a photothermal conversion efficiency up to 60% [3]. In addition, photoactivation of gold NPs has been tested on different types of superficial and localized cancers [4,5]. When using in vitro models, a reduction of more than 70% in cell viability was observed [3,5]. Regarding the 2nd main area, IBEB has participated in several study groups from NATO STO to evaluate the effects of laser dazzle. Within this topic, simulators have been developed [6] and the performance of subjects being dazzled whilst performing tasks requiring concentration, has been assessed using electroencephalography signals [7].
    2024-07Journal article Open access Show more