FM-IB-Artigos em Revistas Internacionais
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Browsing FM-IB-Artigos em Revistas Internacionais by Subject "ABPM"
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- Ambulatory blood pressure, procolagen amino-terminal polypeptide (P-III-P) and hemorreologyc parametersPublication . Moreira, C.; Alcântara, P.; Serejo, Fátima; Gato-Varela, M.; Ramalhinho, V.; Nogueira, José Braz de; Martins e Silva, JoãoThe aim of this work is to study the relationships between blood pressure profile, cardiac manifestations of high blood pressure and P-III-P as an index of fibrosis. We studied hypertensives without other diseases using echocardiography (M and B mode, and Doppler), ABPM using a Spacelabs 9000, and plasma levels of P-III-P. The model ANOVA, one way, was used for the statistical analysis. The level of significance was accepted for p<0.01 (two-tailed probabilities). The 73 hypertensives studied were divided in two subgroups: dippers (49 subjects) and non-dippers (21 subjects). The non-dipper group had an higher degree of left ventricular hypertrophy obtained by the higher measurement of the inter-ventricular septum thickness (p<0.01), posterior wall thickness (p<0.01), and an higher index of left ventricular mass (p<0.01) then the dippers, they also had higher levels of fibrinogen (p<0,01) and higher plasma levels of P-III-P then dippers (p<0.01). It was found a correlation between the fibrinogen, P-III-P levels and index of left ventricular mass (p<0,01). In conclusion, P-III-P might be a marker of tissue lesion, and fibrinogen might be a plasma marker of gravity of hypertension. This gravity can be express by the degree of left ventricular hypertrophy.
- Haemorheologic alterations in hypertensive patients (dipper and no dipper)Publication . Moreira, C.; Saldanha, Carlota; Alcântara, P.; Alcântara, C.; Nogueira, José Braz de; Martins e Silva, JoãoThe 24 hours ABPM has allowed the discrimination of hypertensive patients in dippers and non-dippers. Being the last ones associated with a higher number of cardiac and vascular repercussions. The objective of the present work is to evaluate the haemomeologic alterations in hypertensive patients and to determine if there are differences of haemorheologic parameters between these two groups.
