Browsing by Author "de Alemida, IT"
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- Complete beta-oxidation of valproatePublication . Silva, MFB; Ruiter, JPN; Overmars, H; Bootsma, AH; van Gennip, AH; Jakobs, C; Duran, M; de Alemida, IT; Wanders, RJAThe beta-oxidation of valproic acid (VPA; 2-n-propylpentanoic acid) was investigated in vitro in intact rat liver mitochondria incubated with H-3-labelled VPA. The metabolism of [4,5-H-3(2)]VPA and [2-H-3]VPA was studied by analysing the different acyl-Co
