Browsing by Author "Eleutério, Ana"
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- Synthesis and Friedlander reactions of 5-amino-4-cyano-1,3-oxazolesPublication . Carreiras, Maria do Carmo; Eleutério, Ana; Dias, Catarina; Brito, Maria Alexandra; Brites, Dora; Marco-Contelles, José; Gómez-Sánchez, ElenaThe synthesis of 2-substituted 5-amino-4-cyano-1,3-oxazoles (1-4, 6-11) and the Friedländer-type reaction of compounds 1, 3, 4 is described. Compounds 13-17 are tacrine (18) analogues provided by the Friedländer reaction. The anti-cholinesterase activity of compounds 13, 14, 16 and 17 has been investigated.